AI Summary
Generated by AI for informational purposes only
This is a cream used to treat a skin condition called atopic dermatitis, or eczema. It helps reduce inflammation, itching, and redness on the skin. It should be used with caution during pregnancy and breastfeeding.
Indications
Difamilast ointment is used topically to treat atopic dermatitis, commonly known as eczema.
Composition
0.3% Ointment: Each gram of ointment contains Difamilast INN 3 mg.
1% Ointment: Each gram of ointment contains Difamilast INN 10 mg.
Pharmacology
Difamilast is a phosphodiesterase 4 (PDE4) inhibitor. It increases cyclic adenosine 3',5'-monophosphate (cAMP) concentration and consequently suppresses the production of inflammatory cytokines, exerting effects in treatment of atopic dermatitis.
Dosage & Administration
Important: Do not take any medication without a doctor's prescription. Self-medication can be dangerous.
The usual adult dosage is an appropriate amount of the Difamilast 1% ointment applied to the affected area twice daily. The usual pediatric dosage is an appropriate amount of the Difamilast 0.3% ointment applied to the affected area twice daily.
Contraindications
Difamilast is contraindicated in individuals with a known hypersensitivity to the drug.
Side Effects
Well tolerated in recommended dosage. At higher dosage it may cause mild skin reactions at the site of application, such as redness, burning, or stinging.
Pregnancy & Lactation
Difamilast is not recommended for pregnant women or women who may possibly be pregnant. For breastfeeding, safety profile has not been fully established.
Precautions & Warnings
External use only. Difamilast ointment is not for oral, ophthalmic, or intravaginal use.
If there is any hypersensitivity issue with the use of Difamilast, treatment should be discontinued.
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
The information provided on this page is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
Always consult a qualified healthcare professional before starting, stopping, or changing any medication.
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