AI Summary
Generated by AI for informational purposes only
This eye drop is used to lower high pressure inside the eye, which helps prevent vision loss from glaucoma. It works by reducing the amount of fluid in the eye. It is generally not recommended during pregnancy and should be used with caution while breastfeeding.
Indications
This sterile eye drops is indicated for the treatment of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension who are insufficiently responsive to topical beta blockers.
Pharmacology
Dorzolamide Hydrochloride and Timolol Maleate reduce intraocular pressure (IOP) by combined action. Dorzolamide is human carbonic anhydrase II inhibitor which decreases aqueous humor secretion by slowing the formation of bicarbonate ions with subsequent reduction in sodium and fluid transport. Timolol is a non-selective beta adrenergic receptor blocker that does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anesthetic (membrane stabilizing) activity. It lowers IOP by decreasing the formation of aqueous humor in the ciliary epithelium.
Dosage & Administration
Important: Do not take any medication without a doctor's prescription. Self-medication can be dangerous.
Instill one drop in the conjunctival sac of the affected eye(s) twice daily.
Use in children: Safety and effectiveness in children below the age of 2 years have not been established.
Use in elderly patients: No overall differences in safety and effectiveness have been observed between elderly and other adult patients.
Interaction
Additive hypotension and bradycardia with oral calcium channel blockers, catecholamine-depleting drugs or β-blockers, antiarrhythmics (e.g. amiodarone), digitalis glycosides, parasympathomimetics, narcotics and MAOIs. Additive systemic side effects with oral carbonic anhydrase or β-blockers; avoid concurrent use. Additive systemic β-blockade with CYP2D6 inhibitors (e.g. quinidine, SSRIs) and timolol.
Contraindications
Contraindicated in patients who are hypersensitive to any of the components of this preparation.
Side Effects
Mild burning, ocular hyperemia, blurred vision may occur.
Pregnancy & Lactation
Use in pregnancy: There are no adequate and well-controlled studies in pregnant women. This Eye Drops should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Use in lactation: Caution should be exercised when This Eye Drops is administered to a nursing mother.
Precautions & Warnings
For ophthalmic use only. Patients should remove their contact lenses prior to instilling this preparation and should not insert their lenses until 15 minutes after instillation of the preparation.
Storage Conditions
Store in a cool & dry place, protect from light. Do not use longer than one month after first opening. Keep out of the reach of children.
The information provided on this page is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
Always consult a qualified healthcare professional before starting, stopping, or changing any medication.
All brands listed might have copyright or trademark of their respective owners. Listed information may not be up-to-date or accurate. We do not guarantee the availability, quality, price or safety of any medication. Use at your own risk.
