Cefdinir – Generic Drug Info

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Cefdinir

Third generation Cephalosporins

Generic drug information & available brands

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AI Summary Generated by AI for informational purposes only

This is an antibiotic used for various bacterial infections like pneumonia and bronchitis, as well as infections in the ear, throat, and skin. It works by killing the bacteria causing the infection. It is considered safe to take during pregnancy and while breastfeeding.

Antibiotic — Prescription Required

This medicine is an antibiotic. It must only be used under a doctor's prescription. Misuse or incomplete courses can lead to antibiotic resistance and serious health risks.

Indications

Cefdinir is indicated in-
  • Community Acquired Pneumonia,
  • Acute Exacerbations of Chronic Bronchitis,
  • Acute Maxillary Sinusitis,
  • Pharyngitis/Tonsillitis,
  • Acute Bacterial Otitis Media and
  • Uncomplicated Skin and Skin Structure Infections.

Pharmacology

Cefdinir is a semisynthetic third generation oral cephalosporin antibotic. It has a broad spectrum bactericidal activity against a wide range of common pathogens, including b-lactamase producing strains like Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae, Moraxella catarrhalis, E. coli, Klebsiella pneumoniae, and Proteus mirabilis. As with other cephalosporins, bactericidal activity of Cefexta results from inhibition of cell wall synthesis.

Dosage & Administration

Important:
Do not take any medication without a doctor's prescription. Self-medication can be dangerous.
The total daily dose for all infections is 600 mg. The dosage schedule is given in the following:

Type of infection Dosage Duration
Acute Exacerbations of Chronic Bronchitis 300  mg two times daily or 600 mg once daily 5 to 10 days
Pharyngitis/Tonsillitis
Acute Bacterial Otitis Media
Acute Maxillary Sinusitis 300 mg two times daily or 600 mg once daily 10 days
Community Acquired Pneumonia 300mg two times daily 10 days
Uncomplicated Skin and Skin Structure Infections

Powder for Oral Suspension: The total daily dose for all infections is 14 mg/kg body weight up to a maximum dose of 600 mg per day. The dosage schedule of oral suspension for pediatric patients as follows:
 
Type of infection Dosage Duration
Acute Bacterial Otitis Media 7mg/kg two times or 14 mg/kg once daily 5 to 10 days
Phayngitis/Tonsilitis    
Acute Maxillary Sinusitis 7mg/kg two times or14 mg/kg once daily 10 days
Uncomplicated Skin and Skin Structure Infections 7mg/kg two times daily 10 days

Direction for Reconstitution of Powder for Suspension: Shake the bottle well so that powder does not clog. Add 40 ml (8 x 5 ml spoonful) boiled and cooled water with the provided 5ml spoon to the bottle. Shake well until all powder is dispersed. Reconstituted suspension should be used within 10 days of preparation if kept at room  temperature or within 14 days if kept in a refrigerator. Shake the bottle well before use.

Interaction

Antacids: Cefdinir should be taken at least 2 hours interval of antacid administration.

Iron supplement: Cefdinir should be taken at least 2 hours interval of iron supplement administration.

Probencid: It inhibits the renal excretion of cefdinir.

Contraindications

Cefdinir is contraindicated in patients with known allergy to the cephalosporin class of antibiotics.

Side Effects

Common side effects are Diarrhea, Vaginal moniliasis, Nausea & Vomiting, Headache, Rash etc.

Pregnancy & Lactation

Its pregnancy category is B. But there are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed. After administration of single 600 mg doses Cefdinir was not detected in the breast milk.

Precautions & Warnings

Cefdinir, as with other broad-spectrum antibiotics, should be prescribed with caution in individuals with a history of colitis. In patients with transient or persistent renal insufficiency (creatinine clearance <30 ml/min), the total daily dose of Cefdinir should be reduced.

Storage Conditions

Store at room temperature and protect from light. After reconstitution the suspension can be used within 7 days if kept at room temperature and within 14 days if kept in refrigerator (2-8°C). Always keep the bottle tightly closed.

The information provided on this page is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. All brands listed might have copyright or trademark of their respective owners. Listed information may not be up-to-date or accurate. We do not guarantee the availability, quality, price or safety of any medication. Use at your own risk.

Available Brands

12 found
Brand Strength Type ৳
Adinir
ACME Laboratories Ltd.
300 mg Capsule 45.25
Adinir
ACME Laboratories Ltd.
125 mg/5 ml Powder for Suspension -
Cednir
Eskayef Pharmaceuticals Ltd.
300 mg Capsule 40.00
Cednir DS
Eskayef Pharmaceuticals Ltd.
250 mg/5 ml Powder for Suspension -
Cefexta
UniMed UniHealth Pharmaceuticals Ltd.
300 mg Capsule 57.00
Cefexta
UniMed UniHealth Pharmaceuticals Ltd.
125 mg/5 ml Powder for Suspension -
Cefida
Beximco Pharmaceuticals Ltd.
125 mg/5 ml Powder for Suspension -
Cefida
Beximco Pharmaceuticals Ltd.
300 mg Capsule 45.00
Efdinir
Incepta Pharmaceuticals Ltd.
300 mg Capsule 45.00
Efdinir
Incepta Pharmaceuticals Ltd.
125 mg/5 ml Powder for Suspension -
Ridicef
Navana Pharmaceuticals Ltd.
125 mg/5 ml Powder for Suspension -
Ridicef
Navana Pharmaceuticals Ltd.
300 mg Capsule 45.17
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