Quinine Sulfate – Generic Drug Info

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Quinine Sulfate

Anti-malarial drugs

Generic drug information & available brands

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AI Summary Generated by AI for informational purposes only

This medicine is primarily used to treat malaria when other drugs are not suitable. It works by killing the parasites that cause the infection. It is generally not recommended during pregnancy and should be used with caution while breastfeeding.

Indications

Quinine Sulfate is indicated in-

Uncomplicated, severe and complicated falciparum malaria
Falciparum malaria resistant to other drugs
Prevention of nocturnal muscle cramps
Alleviation of muscle cramps in Thomsen's disease.

Pharmacology

Quinine is believed to interfere with protein metabolism and inhibits nucleic acid synthesis in malarial parasites. Quinine is a highly active blood schizonticide and suppresses the asexual cycle of development of malaria parasites in the erythrocytes. It is effective both as a suppressive drug and in the over clinical attack of malaria.

Dosage & Administration

Important:
Do not take any medication without a doctor's prescription. Self-medication can be dangerous.

Adult:

Oral: 600 mg (of quinine salt) every 8 hours for 7 days.
Parenteral: lf the patient is seriously ill quinine should be given by intravenous infusion. The adult dosage regimen for quinine by infusion is loading dose of 20 mg/kg (up to maximum 1.4 g) of quinine salt infused over 4 hours then after 8-12 hours maintenance dose of 10 mg/kg (up to maximum 700 mg) of quinine salt infused over 4 hours every 8-12 hours (until patient can swallow tablets to complete the 7 days course).

Children:

Oral: Quinine is well tolerated by children. The dosage regimen for quinine by mouth for children is 10 mg/kg (of quinine salt) every 8 hours for 7 days.
Parenteral: The dosage regimen for quinine by intravenous infusion for children is calculated on a mg/kg basis as for adult.

Pregnancy: The adult treatment doses of oral and intravenous quinine given above (including the loading dose) can safely be given to pregnant women.

Contraindications

Hypersensitivity reaction, optic neuritis, in case of black water fever etc.

Side Effects

Cinchonism which includes tinnitus, headache, nausea and visual disturbances. Hematological disorders and skin reaction may occur.

Pregnancy & Lactation

In pregnancy, the quinine is not necessarily contraindicated. It is considered to be safe when used in therapeutic dosage in pregnancy. It is excreted in breast milk in insignificant amount which does not discard the use in lactation.

Precautions & Warnings

Severe heart disease, myasthenia gravis, diabetes mellitus, IV injection should be given slowly. Use of Mefloquine with Quinine sulphate may increase the chance of side effects.

Storage Conditions

Use of Mefloquine with Quinine sulphate may increase the chance of side effects.

The information provided on this page is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. All brands listed might have copyright or trademark of their respective owners. Listed information may not be up-to-date or accurate. We do not guarantee the availability, quality, price or safety of any medication. Use at your own risk.

Available Brands

8 found

Brand	Strength	Type	৳
Albiquin Albion Laboratories Limited	300 mg	Tablet	6.40
Jasoquin Jayson Pharmaceutical Ltd.	300 mg	Tablet	6.44
Jasoquin Jayson Pharmaceutical Ltd.	300 mg/5 ml	Injection	-
Kanaquine Globe Pharmaceuticals Ltd.	300 mg	Tablet	6.40
Kanaquine Globe Pharmaceuticals Ltd.	300 mg/5 ml	Injection	-
Quin Hudson Pharmaceuticals Ltd.	300 mg	Tablet	3.47
Requin Rephco Pharmaceuticals Ltd.	300 mg/5 ml	Injection	10.20
Requin Rephco Pharmaceuticals Ltd.	300 mg	Tablet	3.44

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