AI Summary
Generated by AI for informational purposes only
This medicine is a type of eye drop used to treat fungal infections in the eye. It works by stopping the growth of fungus causing the infection. It should be used with caution during pregnancy and breastfeeding.
Indications
Fluconazole eye drop is indicated in the treatment of fungal corneal ulcers/ keratitis.
Pharmacology
Fluconazole eye drop is a topical ophthalmic solution containing Fluconazole (a bis-triazole derivative) having established therapeutic activity against superficial ocular fungal infections. Fluconazole is fungistatic in action. The drug inhibits cytochrome P-450 14-alfa demethylase in susceptible fungi which leads to alteration of cellular membrane resulting in increased membrane permeability, leakage of essential elements and impaired uptake of precursor molecules to DNA.
Dosage & Administration
Important: Do not take any medication without a doctor's prescription. Self-medication can be dangerous.
Instill 1 drop to be instilled into the affected eye(s) 5 times daily.
Interaction
Fluconazole can alter pharmacokinetics of certain drugs undergoing hepatic metabolism.
Contraindications
The drug is contraindicated in patients with hypersensitivity to azoles.
Side Effects
This drug is generally well tolerated. Eosinophillia has been reported in some patients.
Pregnancy & Lactation
There are no adequate and well-controlled studies in pregnant women. Fluconazole should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Nursing mother should not be given as the drug is excreted in breast milk in concentration similar to plasma.
Precautions & Warnings
Use of fluconazole may result in overgrowth of non-susceptible strains of candida other than Candida albicans
Storage Conditions
Keep out of the reach of children. Store in a cool, dry place, away from heat and direct light. Do not use more than 4 weeks after opening the bottle.
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Always consult a qualified healthcare professional before starting, stopping, or changing any medication.
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