Irigon – Glycine

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Irigon

1.5% Irrigation Solution Irrigation Solution used in Urological Surgery
Glycine · Beximco Pharmaceuticals Ltd.
EN বাং
AI Summary Generated by AI for informational purposes only

This is a sterile solution used by doctors to rinse or irrigate the bladder and urinary tract during certain surgical procedures. It helps keep the surgical area clear for the surgeon. Its use during pregnancy is determined by the doctor based on the medical procedure.

Indications

This is indicated as irrigating fluid of choice in:
  • Transurethral resection of prostate.
  • Endoscopic procedures within the urinary tract.
  • Urinary bladder surgery etc.

Pharmacology

Glycine irrigation solution contains glycine which is an amino acid and a non-electrolyte. It is therefore non-conductive and suitable for irrigation purpose. Glycine Irrigation Solution minimizes the risk of intravascular haemolysis which can occur from absorption of plain water. Glycine Irrigation Solution is rapidly degraded in the liver by glycine oxidase.

Dosage

The total volume of solution used for irrigation depends on the judgment of the attending surgeon. Height from the operating table of 60 cm (approx. 2ft) is likely to cause increased intravascular absorption of glycine.

Administration

Administration Procedure:
  • Check infusion set and infusion solution prior to use
  • Pull moderately to tear off the protective cover of the Eurohead
  • Hold lightly the Eurohead but not the bag
  • Open the flow regulator fully and hold the giving set on the top white area, but not the membrane venting region
  • Insert the spike of the administration set to the Eurohead and fit the connector of the administration set firmly to the needle
  • Gradually allow the fluid to flow down to the needle tip and close
  • Remove the protective cover of the needle
  • Locate the veinpuncture site and clean the site with an antiseptic solution, and then insert the needle
  • Securely tape the puncture site
  • Securely tape the wings and tubing
  • Start infusion while adjusting drip speed

Interaction

Additives may be incompatible. When introducing additives, use aseptic technique, mix thoroughly and do not store.

Contraindications

Glycine Irrigation Solution is not for injection in any route. It is contraindicated in patients with anuria.

Side Effects

Large intravenous doses of glycine are known to cause nausea and salivation. Other consequences of systemic absorption of glycine include electrolyte loss, diuresis, edaema, thirst, dehydration, cardiovascular and pulmonary disorders.

Precautions & Warnings

Patients with cardiovascular disease should be evaluated after transurethral resection of prostate using glycine. Care should be exercised if the liver or kidney is impaired. Aseptic technique is essential while using glycine. Unused portion should be discarded. Do not use if the bottle is leaking, solution is cloudy, contains particles or after expiry date.

Storage Conditions

Store at controlled room temperature, protect from light and heat

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