AI Summary
Generated by AI for informational purposes only
These are eye drops used to widen the pupil for eye exams or to treat certain eye inflammations. It works by relaxing the muscles of the eye. It should be used with caution during pregnancy and while breastfeeding.
Indications
Homatropine Hydrobromide eye drops is indicated for use as a mydriatic and cycloplegic.
Pharmacology
Homatropine is a competitive muscarinic receptor antagonist with a bulky aromatic group in place of the acetyl group of acetylcholine. It is expected to act in similar manner as atropine, producing similar parasympatholytic effects. By blocking muscarinic receptors and cholinergic signalling pathways, homatropine blocks the response of the iris sphincter muscle and cause the pupil to become unresponsive to light upon dilation or mydriasis. It also blocks the accommodative muscle of the ciliary body to cholinergic stimulation.
Dosage & Administration
Important: Do not take any medication without a doctor's prescription. Self-medication can be dangerous.
For refraction: Instill two drops in the eye(s) and repeat 2-3 times at 5-10 minute intervals. For therapy: Instill 1-2 drops in the eye(s) every 3-4 hours. Use in children: Should not be used in children below the age of 3 months.
Interaction
Effects may be increased by drugs with antimuscarinic effect such as; some antihistamines; phenothiazines; antipsychotics; TCAs; MAOIs or parasympathomimetics.
Contraindications
Contraindicated in patients with closed-angle glaucoma or with a narrow angle between the iris and the cornea.
Side Effects
Hypersensitivity may occur as conjunctivitis.
Pregnancy & Lactation
There are no adequate and well-controlled studies in pregnant women. Matropin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether Homatropine is excreted in human milk. Caution should be exercised when Matropin is administered to a nursing mother.
Precautions & Warnings
Should be used with caution in patients with prostatic enlargement and in patients suffering from paralytic ileus or pyloric stenosis.
Storage Conditions
Store in a cool & dry place, protect from light. Do not use longer than 30 days after first opening. Keep out of the reach of children.
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Always consult a qualified healthcare professional before starting, stopping, or changing any medication.
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