AI Summary
Generated by AI for informational purposes only
This is a pain relief medicine used through the rectum to reduce pain, swelling, and joint stiffness. It is often used for conditions like arthritis. It is not safe during the last three months of pregnancy and should be used with caution while breastfeeding.
Indications
Indomethacin is indicated for the treatment of rheumatoid arthritis, ankylosing spondylitis, osteoarthritis (degenerative joint disease), gout, acute non-articular rheumatism (bursitis, synovitis, tendinitis).
Pharmacology
Indomethacin is a non-steroidal anti-inflammatory drug (NSAID) having properties of antipyretic and analgesic effects. A great number of pharmacological studies have proved that Indomethacin has strong anti-inflammatory, analgesic and antipyretic properties. Unlike the corticosteroids, the effect of Indomethacin is not related to the pituitary gland or the adrenals.
Dosage & Administration
Important: Do not take any medication without a doctor's prescription. Self-medication can be dangerous.
100 mg at night and in the morning if required.
Interaction
It may interact with anticoagulants, lithium, diuretics, Beta-blockers, diflunisal, aspirin, probenecid and sulfonylureas.
Contraindications
It is contraindicated in previously hypersensitive patient.
Side Effects
Headache, usually in the morning and mild vertigo may occur during the early weeks of therapy. These symptoms are transient and usually disappear with continued use or by reduction of the dose. Gastrointestinal reactions such as nausea, vomiting, diarrhea, epigastric and abdominal pain are often due to large doses of the drug and disappear when the dose is reduced.
Pregnancy & Lactation
Not recommended for pregnant women, because at the present time clinical studies are insufficient.
Use in Special Populations
Use in children: Not recommended for children.
Storage Conditions
Keep in a cool place, away from light & moisture. Keep out of the reach of children.
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Always consult a qualified healthcare professional before starting, stopping, or changing any medication.
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