AI Summary
Generated by AI for informational purposes only
This is a strong antibiotic tablet for treating various bacterial infections like pneumonia and bronchitis. It is generally not considered safe to use during pregnancy and breastfeeding.
Antibiotic — Prescription Required
This medicine is an antibiotic. It must only be used under a doctor's prescription. Misuse or incomplete courses can lead to antibiotic resistance and serious health risks.
Indications
Moxifloxacin tablet is indicated for the treatment of acute bacterial sinusitis, acute exacerbation of chronic bronchitis, community acquired pneumonia, uncomplicated & complicated skin and skin structure infections, complicated intra-abdominal infections and pelvic inflammatory disease.
Pharmacology
Moxifloxacin is a 4th generation synthetic broad spectrum, fluoroquinolone class of antibacterial drug. It has activity against a wide range of gram-positive, gram-negative, anaerobic and atypical bacteria including Mycoplasma pneumoniae. It acts by inhibiting topoisomerase II (DNA gyrase) and topoisomerase IV which are necessary for bacterial DNA replication, transcription & repair.
Dosage & Administration
Important: Do not take any medication without a doctor's prescription. Self-medication can be dangerous.
Acute bacterial sinusitis: 400 mg once daily 7-10 days. Acute bacterial exacerbation of chronic bronchitis: 400 mg once daily 5-10 days. Community-acquired pneumonia: 400 mg once daily 7-14 days. Uncomplicated skin and skin structure infections: 400 mg once daily 7 days. Complicated skin and skin structure infections: 400 mg once daily 7-21 days. Complicated intra-abdominal infections: 400 mg once daily 5-14 days. Pelvic inflammatory disease: 400 mg once daily 14 days.
Interaction
Moxifloxacin absorption is decreased when administered with antacids, sucralfate, multivitamins, and multivalent cations (e.g. iron or zinc). Moxifloxacin may enhance the risk of convulsions with NSAIDs and bleeding with warfarin. So concomitant use of Moxifloxacin with them should be avoided.
Contraindications
It is contraindicated in patients with a history of hypersensitivity to Moxifloxacin or other quinolones.
Side Effects
Common side effects of Moxifloxacin include nausea, vomiting, diarrhea, headache and dizziness.
Pregnancy & Lactation
US FDA pregnancy category C. Moxifloxacin is not recommended during pregnancy & lactation.
Precautions & Warnings
Moxifloxacin may cause an increased risk of tendinitis and tendon rupture. It should be discontinued if pain or inflammation in a tendon occurs. It should not be used in patients with known prolongation of the QT interval, patients with uncorrected hypokalemia, and patients with receiving Class IA or Class III antiarrhythmic agents
Use in Special Populations
Renal or hepatic impaired patients: No dose adjustment is necessary for patients with renal or hepatic impairment.
Pediatric patients: Safety and effectiveness of Moxifloxacin in pediatric patients and adolescent less than 18 years of age have not been established.
Storage Conditions
Keep in a dry place, away from light and heat. Keep out of the reach of children.
The information provided on this page is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
Always consult a qualified healthcare professional before starting, stopping, or changing any medication.
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