AI Summary
Generated by AI for informational purposes only
This medicine helps control asthma and allergy symptoms. It works by reducing swelling in the airways, making it easier to breathe. It is generally not considered safe during pregnancy or breastfeeding.
Indications
Pranlukast is indicated for asthma and allergic rhinitis symptoms.
Pharmacology
Pranlukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor in the human airway. It inhibits the actions of LTD4 at the CysLT1 receptor and prevents airway edema, smooth muscle contraction and enhanced secretion of thick, viscous mucus.
Dosage & Administration
Important: Do not take any medication without a doctor's prescription. Self-medication can be dangerous.
Adults: Take 2 tablets (225 mg) at a time, twice a day after breakfast and dinner. The dosage may be adjusted according to your age and symptoms. Strictly follow the instructions. Use in Children & Adolescents: There was a substantial benefit of adding pranlukast to usual therapy in asthmatic children.
Interaction
Concurrent use with warfarin and other anticoagulants may cause an increase in prothrombin time.
Contraindications
Pranlukast is contraindicated in acute asthma attacks and hepatic impairment/cirrhosis.
Side Effects
Headache, increased incidence of respiratory tract infection, GI disturbances, induced generalized pain, fever, myalgia and arthralgia.
Pregnancy & Lactation
Use of pranlukast is not associated with an increased risk of pregnancy loss, gestational diabetes, preeclampsia, low maternal weight, preterm delivery, low apgar scores and reduced measures of birth length in infants. Slightly decreased birth weight in infants born to pranlukast users could be attributed to maternal asthma severity/control.
Precautions & Warnings
Should be cautious regarding the patients with renal impairment. Possible elevations in liver enzymes can happen. Withdraw treatment in patients showing signs consistent with Churg-Strauss syndrome.
Storage Conditions
Keep below 30°C temperature, protected from light & moisture. Keep all medicines out of reach of children.
The information provided on this page is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
Always consult a qualified healthcare professional before starting, stopping, or changing any medication.
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