AI Summary
Generated by AI for informational purposes only
This antiviral eye ointment is used to treat eye infections caused by the herpes virus. It is generally considered safe for use during pregnancy. It should be used with caution while breastfeeding.
Antibiotic — Prescription Required
This medicine is an antibiotic. It must only be used under a doctor's prescription. Misuse or incomplete courses can lead to antibiotic resistance and serious health risks.
Indications
Acyclovir is indicated for the treatment of Herpes simplex keratitis.
Pharmacology
Acyclovir is an antiviral agent which is highly active in vitro against Herpes simplex (HSV) types I and II and Varicella zoster viruses, but its toxicity to mammalian cells is low. Acyclovir is phosphorylated to the active compound Acyclovir triphosphate after entry into herpes infected cell. The first step in this process requires the presence of the viral-coded thymidine kinase. Acyclovir triphosphate acts as an inhibitor of and substrate for the herpes specified DNA polymerase preventing further viral DNA synthesis without affecting normal cellular processes.
Dosage & Administration
Important: Do not take any medication without a doctor's prescription. Self-medication can be dangerous.
The dosage for all age groups is the same. A 10 mm ribbon of the ointment should be placed inside the lower conjunctival sac five times a day at approximately four hourly intervals. Treatment should continue for at least 3 days after healing
Interaction
No clinically significant interactions have been identified.
Contraindications
Acyclovir is contraindicated in patients known to be hypersensitive to Acyclovir or Valacyclovir
Side Effects
Very common: Superficial punctate keratopathy. This did not necessitate an early termination of therapy and healed without apparent sequelae. Common: Transient mild stinging of the eye occurring immediately following application, conjunctivitis. Rare: Blepharitis.
Pregnancy & Lactation
Pregnancy category B. There are no adequate and well-controlled studies of Acyclovir in pregnant women. It is not known whether topically applied Acyclovir is excreted in breast milk.
Precautions & Warnings
The recommended dosage, frequency of applications, and length of treatment should not be exceeded.
Overdose Effects
No adverse effects would be expected if the entire contents of the tube containing 90 mg Acyclovir were ingested orally.
Storage Conditions
Store in a cool and dry place. Keep away from light. Keep out of reach of children. Do not touch the tip of the tube since this may contaminate the product. After one month of the opening do not use the medicine of tube.
The information provided on this page is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
Always consult a qualified healthcare professional before starting, stopping, or changing any medication.
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