Relitch – Betamethasone + Phenylephrine + Lignocaine

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Relitch

0.05%+0.1%+2.5% Rectal Ointment 4-Quinolone preparations, Phlebotonic & Vascular protecting preparation
Betamethasone + Phenylephrine + Lignocaine · Drug International Ltd.
EN বাং
AI Summary Generated by AI for informational purposes only

This medicine is used to treat the symptoms of piles or hemorrhoids. It reduces swelling and pain, shrinks swollen veins, and numbs the area to relieve itching. It should be used during pregnancy and breastfeeding only on a doctor's advice.

Indications

This preparation rectal ointment is indicated for relief of the symptoms of-
  • Itching,
  • Irritation,
  • Discomfort or pain associated with local non-infective anal or peri-anal conditions such as external hemorrhoids.

Composition

The composition of this rectal ointment is given below:
  • Betamethasone (as 17 valerate) 0.05%
  • Phenylephrine hydrochloride 0.1%
  • Lignocaine hydrochloride 2.5%

Pharmacology

Betamethasone is a corticosteroid with mainly glucocorticoid activity. It induces phospholipase A2 inhibitory lipase (lipocortins) and sequentially inhibits the release of arachidonic acid, thereby depressing the formation, release, and activity of prostaglandins, leukotrienes, and other inflammatory mediators.

Phenylephrine is a sympathomimetic with mainly direct effects on alpha-adrenergic receptors and weak beta-adrenergic activity. It causes vasoconstriction of the arterioles of the nasal mucosa and conjunctiva; activates the dilator muscle of the pupil to cause contraction; produces vasoconstriction of arterioles in the body and produces systemic arterial vasoconstriction.

Lidocaine alters signal conduction in neurons by blocking the fast voltage-gated Na+ channels in the neuronal cell membrane responsible for signal propagation. With sufficient blockage, the membrane of the postsynaptic neuron will not depolarize and will thus fail to transmit an action potential.

Dosage & Administration

Important:
Do not take any medication without a doctor's prescription. Self-medication can be dangerous.
A course of treatment should be limited to 7 days. Apply a small amount of ointment two or three times a day initially, using the applicator if internal administration is required. When inflammation is subsiding, once-daily application is sufficient in most cases. Or as directed by the physician.

Contraindications

Primary cutaneous viral infections (e. g. herpes simplex, chickenpox). Hypersensitivity to any components of the drug. The use of this ointment is not indicated in the treatment of primarily infected skin lesions caused by infection with fungi (e. g. candidiasis, tinea); or bacteria (e. g. impetigo).

Side Effects

Signs of hypersensitivity may appear. Prolonged and intensive treatment with highly active corticosteroid preparations may cause local atrophic changes in the skin.

Pregnancy & Lactation

There is inadequate evidence of safety in human pregnancy.

Precautions & Warnings

Long-term continuous therapy should be avoided where possible, particularly in infants and children, as adrenal suppression can occur.

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

The information provided on this page is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. All brands listed might have copyright or trademark of their respective owners. Listed information may not be up-to-date or accurate. We do not guarantee the availability, quality, price or safety of any medication. Use at your own risk.

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