AI Summary
Generated by AI for informational purposes only
This herbal medicine is often taken to help improve mood, ease mild to moderate depression, and address sleep problems like insomnia. It works by influencing brain chemicals that affect your feelings. While generally safe, some people might experience dry mouth or dizziness. It is not recommended for use during pregnancy or while breastfeeding.
Indications
St. John’s Wort is indicated in-
Depression
Insomnia
Seasonal Affective Disorder (SAD)
Obsessive Compulsive Disorder (OCD)
Description
Jonort is a unique preparation of standardized extract of St. john’s Wort, which is widely used as effective herbal medicine in the treatment of depression. The major active constituents of St. john’s Wort are hypericin, hyperforin, hyperoside, quercitrin and rich in vitamin C. Jonort possesses antidepressant activity which inhibits re-uptake of neurotransmitters such as serotonin, dopamine, noradrenaline, γ-aminobutyric acid (GABA) and L-glutamate. It has also inhibiting activity of Monoamine oxidase (MAO) and Catechol-O-methyltransferase (COMT).
Pharmacology
St. John’s Wort is an herb which is most commonly used to treat for mild to moderate depression and conditions that sometimes go along with depression such as anxiety, tiredness, loss of appetite and insomnia. The main components of St. John’s Wort are Hypericin and Hyperforin which are responsible for its effects against depression. Although the exact mechanism of action of St. John’s Wort is unknown but it may inhibit the reuptake of Serotonin and Noradrenaline, inhibit Monoamine Oxidase (MAO), up-regulate Serotonin receptor, and reduce depression.
Dosage & Administration
Important: Do not take any medication without a doctor's prescription. Self-medication can be dangerous.
The recommended dose of St. John’s Wort capsule in adults is 1 capsule 3 times daily or as prescribed by the physician.
Interaction
Symptoms of St. John’s Wort overdose may include dry mouth, dizziness and diarrhea.
Side Effects
St. John’s Wort is generally safe for most people. It sometimes may cause dry mouth, dizziness, constipation and diarrhea.
Pregnancy & Lactation
St. John’s Wort is not recommended for use during pregnancy.Because of the possible risk to the infant, breast-feeding while using this drug is not recommended.
Precautions & Warnings
St. John’s Wort should be used cautiously with drugs metabolized by Cytochrome P450 and drugs that lower the seizure threshold.
Storage Conditions
Keep out of reach of the children. Keep away from direct sunlight; store in a cool and dry place.
The information provided on this page is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
Always consult a qualified healthcare professional before starting, stopping, or changing any medication.
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