AI Summary
Generated by AI for informational purposes only
This medicine is often used to help men with erectile dysfunction or when they have a decreased desire for sex. It might also be used to overcome feelings of exhaustion or fatigue. It is generally not considered safe for use during pregnancy or while breastfeeding, and people with liver or kidney problems should avoid it.
Indications
Yohimbine is indicated in erectile dysfunction, loss of libido & exhaustion.
Description
The medicinal part of yohimbe is the bark. This evergreen tree grows up to 30 m in height. The bark is gray-brown and the inner fracture is reddish brown and grooved. It tastes bitter and the plant is odorless. The tree grows in the jungles of West Africa, Cameroon, Congo and Gabon. The main alkaloid present in the bark is Yohimbine.
Pharmacology
Yohimbe is a potent alpha-2 adrenoceptor blocker and a weak alpha-1 adrenergic antagonist with some antidopaminergic properties. Yohimbe interacts with adrenoceptors that are selectively stimulated by clonidine, alpha-methylnorepinephrine, tramazoline, guanabenz & guanfacin. It also interacts with compounds that are nonselectively stimulated by norepinephrine and epinephrine. Yohimbe has a modest beneficial effect in the management of erectile dysfunction. Because of the alpha-2 adrenergic blockade, the drug is an effective treatment for sexual disorders such as decreased libido and decreased sexual response, caused by selective serotonin reuptake inhibitors.
Dosage & Administration
Important: Do not take any medication without a doctor's prescription. Self-medication can be dangerous.
1 capsule 3 times daily or as advised by the physician
Interaction
Theoretically, Yohimbe may counteract the hypotensive effect of antihypertensive medications, resulting inadequate blood pressure control. It may potentiate pharmaceutical MAO-inhibitors
Contraindications
The drug should not be used by patients with liver and kidney diseases, chronic inflammation of the sexual organs or prostate gland or with a history of gastric or duodenal ulcers
Patients taking Yohimbe should avoid alcohol ingestion
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
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