Eluxan

75 mg Tablet Carboxylic acids and derivatives, Prokinetic drugs
Eluxadoline · Ziska Pharmaceuticals Ltd.
EN বাং
৳125.00
per unit
AI Summary Generated by AI for informational purposes only

এই ঔষধটি প্রাপ্তবয়স্কদের ডায়রিয়াযুক্ত ইরিটেবল বাওয়েল সিনড্রোম এর চিকিৎসায় ব্যবহৃত হয়। এটি পেটের ব্যথা কমাতে এবং মলের ঘনত্ব ঠিক করতে সাহায্য করে। গর্ভাবস্থায় এর ব্যবহার নিয়ে যথেষ্ট তথ্য নেই এবং স্তন্যদানকালে এটি ব্যবহার করা উচিত নয়।

Indications

Eluxadoline is indicated in adults for the treatment of irritable bowel syndrome with diarrhea (IBS-D).

Pharmacology

Eluxadoline is a mu-opioid receptor agonist, kappa opioid receptor agonist & delta opioid receptor antagonist. Eluxadoline works directly in intestine to reduce peristalsis, also makes the nerves in intestine less sensitive to stimulation.

Dosage & Administration

Important:
Do not take any medication without a doctor's prescription. Self-medication can be dangerous.
The recommended dose is 75 mg tablet taken orally twice daily with food. Patients who develop severe constipation for more than 4 days have to discontinue the drug. If a dose is missed, patient should take the next dose at the regular time and avoid taking two doses at a time.

Pediatric Use: Safety and effectiveness in pediatric patients have not been established.

Hepatic Impairment: It is contraindicated in patients with severe hepatic impairment.

Interaction

Oral Contraceptive, Cyclosporine, Probenecid, Rosuvastatin.

Contraindications

Known or suspected biliary duct obstruction, sphincter of oddi disease or dysfunction & pancreatitis.

Side Effects

Most common adverse reactions are constipation, nausea and abdominal pain.

Pregnancy & Lactation

Pregnancy: Not established.
Lactation: Not established.

Precautions & Warnings

Sphincter of Oddi spasm and Pancreatitis.
Patients who should be monitored closely-
  • without a gallbladder
  • with new or worsening abdominal pain
  • with nausea and vomiting
  • with acute biliary pain
  • with liver or pancreatic enzyme elevation

Storage Conditions

Store in a cool & dry place, protect from light. Keep out of the reach of children.

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