AI Summary
Generated by AI for informational purposes only
এই ওষুধটি শরীরের অতিরিক্ত পানি এবং চোখের চাপ কমাতে সাহায্য করে। এটি গ্লুকোমা, শরীর ফুলে যাওয়া এবং উচ্চতাজনিত অসুস্থতা প্রতিরোধে ব্যবহৃত হয়। গর্ভাবস্থায় এটি সাধারণত ব্যবহার করা উচিত নয় এবং স্তন্যদানকালে সতর্কতার সাথে ব্যবহার করতে হয়।
Indications
Acetazolamide is indicated in open angle glaucoma, secondary glaucoma and as an adjuvant in the treatment of edema and epilepsy.
Pharmacology
Acetazolamide is a carbonic anhydrase inhibitor. This enzyme catalyzes the reversible reaction involving the hydration of carbon-di-oxide and the dehydration of carbonic acid. In the eye, this inhibitory action of Acetazolamide decreases the secretion of aqueous humor and results in a drop in intraocular pressure, a reaction considered desirable in case of glaucoma. Inhibition of carbonic anhydrase in the central nervous system appears to retard abnormal paroxysmal and excessive discharge from central nervous system neurons. So, Acetazolamide is also used as an adjuvant in the treatment of epilepsy.
Dosage & Administration
Important: Do not take any medication without a doctor's prescription. Self-medication can be dangerous.
Adults : Initially 250 mg (1 tablet) 4 times daily. Dose should be adjusted later with individual need. Children : ½ to 2 tablets in divided doses.
In intraocular pressure: 1 tablet 6 hourly. In acute condition, dose should be started with 2 tablets followed by 1 tablet 6 hourly or as directed by the physician
Contraindications
Acetazolamide is contraindicated in cases of marked kidney and liver diseases or dysfunction, in situations in which sodium and or potassium blood serum levels decreased. Acetazolamide is also contraindicated in patients with chronic noncongestive angle closure glaucoma
Side Effects
Common side effects are headache, drowsiness, dizziness, fatigue, anorexia, polyurea, insomnia, gastrointestinal upset.
Pregnancy & Lactation
There are no adequate and well controlled studies in pregnant women and neonates. So, Acetazolamide should be used with care in those physiological conditions.
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
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