AI Summary
Generated by AI for informational purposes only
This medicine helps to open up the airways in the lungs, making it easier to breathe. It is used to prevent and manage symptoms of asthma and other long-term lung diseases. It should be used with caution during pregnancy and breastfeeding.
Indications
Bambuterol is indicated for
Bronchial asthma
Chronic bronchitis
Emphysema
Other lung diseases where bronchospasm is a complicating factor.
Pharmacology
Bambuterol, a prodrug of terbutaline, is a long acting ß2 adrenergic receptor agonist used in the treatment of asthma. Bambuterol is an adrenergic ß2 receptor agonist which predominantly stimulates ß2 receptor, thus producing relaxation of bronchial smooth muscle, inhibition of release of endogenous spasmogens, inhibition of edema caused by endogenous mediators & increased mucocilliary clearance.
Dosage & Administration
Important: Do not take any medication without a doctor's prescription. Self-medication can be dangerous.
Children 2-5 years: The recommended normal dose 10 mg (10 ml syrup).
Children 6-12 years: The recommended normal dose 10 mg (10 ml syrup). The dose may be increased to 20 mg.
Adult: The recommended initial dose 10 mg. The dose may be increased to 20 mg after 1-2 weeks depending on the clinical effect.
Although no teratogenic effects have been observed in animal after administration of bambuterol, caution is recommended during first trimester of pregnancy. It is not known whether bambuterol or intermediary metabolites pass over to breast milk, so caution is recommended if bambuterol is administered to patients who are breast feeding. Terbutalin passes over to breast milk but an influence on the child is unlikely with therapeutic doses. Transient hypoglycemia has been reported in new born pre-term infants after maternal ß2 agonist treatment.
Precautions & Warnings
Dose should be reduced in patients with severely impaired renal function, patiensts with genetic deficiencies of plasma cholineterase, patient with severe ischemic heart disease.
Overdose Effects
No case of bambuterol overdosage has yet been reported in human. It is likely that overdosing would result in high levels of terbutaline & therefore the same symptoms & signs may include: headache, anxiety, tremor, nausea, tonic muscle cramps, palpitations, tachycardia & cardiac arrythmias. A fall in blood pressure sometimes occurs after terbutaline overdosage.
Laboratory findings: hyperglycaemia and lactacidosis sometimes occur. High doses of ß2-agonists may cause hypokalemia as a result of redistribution of potassium.
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
The information provided on this page is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
Always consult a qualified healthcare professional before starting, stopping, or changing any medication.
All brands listed might have copyright or trademark of their respective owners. Listed information may not be up-to-date or accurate. We do not guarantee the availability, quality, price or safety of any medication. Use at your own risk.
