Gentian Violet – Generic Drug Info

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Gentian Violet

Crystal violet/ Gentian violet preparations

Generic drug information & available brands

AI Summary Generated by AI for informational purposes only

এটি ত্বকের জন্য একটি অ্যান্টিসেপটিক তরল। এটি ছত্রাকজনিত ইনফেকশনের চিকিৎসায় ব্যবহৃত হয়। গর্ভাবস্থায় বা স্তন্যদানকালে এটি সাধারণত ব্যবহার করার পরামর্শ দেওয়া হয় না।

Indications

Topical antiseptic as first aid to help prevent infection in minor cuts, scrapes and burns.

Pharmacology

In aqueous solutions Gentian violet (GV) dissociates into positive (GV+)and negative ions (Cl-) that penetrate through the wall and membrane of both gram-positive and gram-negative bacterial cells. The GV+ interacts with negatively charged components of bacterial cells including the lipopolysaccharide (on the cell wall), the peptidoglycan and DNA. A similar cell penetration and DNA binding process is thought to take place for fungal cells as well. Because Gentian violet is a mutagen and mitotic poison, cell growth is consequently inhibited. A photodynamic action of gentian violet, apparently mediated by a free-radical mechanism, has recently been described in bacteria and in the protozoan T. cruzi. Evidence also suggests that gentian violet dissipates the bacterial (and mitochondrial) membrane potential by inducing permeability. This is followed by respiratory inhibition. This anti-mitochondrial activity might explain gentian violet's efficacy towards both bacteria and yeast with relatively mild effects on mammalian cells.

Dosage & Administration

Important:
Do not take any medication without a doctor's prescription. Self-medication can be dangerous.
Clean the affected area and apply a small amount of this product on the area 1 to 3 times daily. May be covered with a sterile bandage.

Interaction

There are no known drug interactions and none well documented.

Contraindications

Do not apply to an ulcerative lesion as this may cause tattoing of the skin.

Side Effects

Redness, irritation, swelling or pain persists or increases of if infection occurs.

Pregnancy & Lactation

Pregnancy Category- Not Classified. FDA has not yet classified the drug into a specified pregnancy category.

Precautions & Warnings

Stop use if the condition persists or gets worse. Do not use longer than 1 week.

The information provided on this page is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. All brands listed might have copyright or trademark of their respective owners. Listed information may not be up-to-date or accurate. We do not guarantee the availability, quality, price or safety of any medication. Use at your own risk.

Available Brands

4 found
Brand Strength Type
2% Topical Solution -
2% Topical Solution -
1% Topical Solution -
2% Topical Solution -
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