L-Ornithine L-Aspartate – Generic Drug Info

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L-Ornithine L-Aspartate

Digestive Enzyme

Generic drug information & available brands

EN বাং

AI Summary Generated by AI for informational purposes only

This medicine supports liver function by helping to remove harmful toxins from the blood. It is commonly prescribed for various liver diseases. Use during pregnancy or while breastfeeding should only be done under a doctor's supervision.

Indications

L-Ornithine L-Aspartate is indicated for the treatment of Hepatic Encephalopathy, Acute Liver Failure, Hyperammonemia due to Acute and Chronic Hepatitis, Fatty Liver, Alcoholic Liver damage, Adjunct to hepatotoxic drugs, Liver Cirrhosis, Post hepatitis convalescence etc.

Pharmacology

L-Ornithine L-Aspartate is a stable combination of two important endogenous Amino Acids, L-Ornithine and L-Aspartate. After administration, it quickly breaks down into L-Ornithine and L-Aspartate. L-Ornithine being a substrate of urea cycle, converts toxic ammonia into non-toxic urea which is eliminated via kidneys, helping the diseased liver to carry out its normal function smoothly (detoxification). The process lowers the elevated level of ammonia in blood (hyperammonemia) which is a common problem in most of the liver diseases. L-Aspartate is an essential component of citric acid cycle which liberates energy (ATP), and thus helps in regeneration of damaged liver cells.

Dosage & Administration

Important:
Do not take any medication without a doctor's prescription. Self-medication can be dangerous.

Sachet: 1-2 sachets granules is dissolved in a large amount of fluid (e.g. in a glass of water or juice) and is taken orally 3 times a day during or after meals.

Injection (Infusion Concentrate): The recommended dose is up to 20 gm (4 ampoules daily). In case of loss of consciousness (pre-coma) and clouding of consciousness (coma) up to 8 ampoules within 24 hours, depending on the severity of the condition.

Administrations-

L-Ornithine L-Aspartate infusion concentrate can be added to any of the conventional intravenous fluids (0.9% Sodium Chloride, 5% Dextrose and Ringer's lactate etc.)
The normal dilution rate is 1 ampoule per 100 ml of I.V. fluid. However, the dose should not exceed 6 ampoules per 500 ml infusion. The solution mixtures were stable up to 24 hours.
Infusion Rate: 5 gm/h at maximum.

Interaction

No data regarding the interactions of L-Ornithine L-Aspartate was found.

Side Effects

Very rarely side effects like nausea and vomiting occur. These side effects are usually transient and do not necessitate the withdrawal of the drug.

Pregnancy & Lactation

The administration in pregnancy and lactation should be avoided.

Precautions & Warnings

Monitoring of serum and urinary urea levels at regular intervals should be done.

Storage Conditions

Store in a cool and dry place, keep away from light.

The information provided on this page is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. All brands listed might have copyright or trademark of their respective owners. Listed information may not be up-to-date or accurate. We do not guarantee the availability, quality, price or safety of any medication. Use at your own risk.

Available Brands

10 found

Brand	Strength	Type	৳
Hepaclin Incepta Pharmaceuticals Ltd.	5 gm/10 ml	IV Injection	-
Hepaclin Incepta Pharmaceuticals Ltd.	3 gm/sachet	Oral Powder	-
Hepaclin Incepta Pharmaceuticals Ltd.	150 mg	Tablet	18.00
Hepagurd Beximco Pharmaceuticals Ltd.	3 gm/sachet	Oral Powder	-
Hepalola Total Herbal & Nutraceuticals	550 mg	Tablet	20.00
HepaMerz Mundipharma (BD) Pvt. Ltd.	5 gm/sachet	Oral Powder	-
Heparest Everest Pharmaceuticals Ltd.	3 gm/sachet	Oral Powder	-
Heplol Square Pharmaceuticals PLC	150 mg	Tablet	15.00
Lola Jenphar Bangladesh Ltd.	3 gm/sachet	Oral Powder	-
Oliver Beacon Pharmaceuticals PLC	150 mg	Tablet	15.00

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