Retapamulin – Generic Drug Info

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Retapamulin

Topical Antibiotic preparations

Generic drug information & available brands

EN বাং

AI Summary Generated by AI for informational purposes only

এটি একটি অ্যান্টিবায়োটিক মলম যা ত্বকের ব্যাকটেরিয়া জনিত সংক্রমণ সারাতে চামড়ার উপরে লাগানো হয়। এটি ব্যাকটেরিয়ার বৃদ্ধি থামিয়ে দেয়। গর্ভাবস্থায় এটি ব্যবহার করা সাধারণত নিরাপদ, তবে স্তন্যদানকালে সতর্ক থাকা উচিত।

Indications

Retapamulin is indicated for use in adults and pediatric patients aged 9 months and older for the topical treatment of impetigo (up to 100 cm 2 in total area in adults or 2% total body surface area in pediatric patients aged 9 months or older) due to Staphylococcus aureus (methicillin-susceptible isolates only) or Streptococcus pyogenes. Safety in patients younger than 9 months has not been established. To reduce the development of drug-resistant bacteria and maintain the effectiveness of Retapamulin and other antibacterial drugs, Retapamulin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.

Pharmacology

Retapamulin selectively inhibits bacterial protein synthesis by interacting at a site on the 50S subunit of the bacterial ribosome through an interaction that is different from that of other antibiotics. This binding site involves ribosomal protein L3 and is in the region of the ribosomal P-site and peptidyl transferase center. By virtue of binding to this site, pleuromutilins inhibit peptidyl transfer, block P-site interactions, and prevent the normal formation of active 50S ribosomal subunits. Retapamulin is bacteriostatic against Staphylococcus aureus and Streptococcus pyogenes at the Retapamulin in vitro minimum inhibitory concentration (MIC) for these organisms.

Dosage & Administration

Important:
Do not take any medication without a doctor's prescription. Self-medication can be dangerous.

A thin layer of Topibac should be applied to the affected area (up to 100 cm² in total area in adults or 2% total body surface area in pediatric patients aged 9 months or older) twice daily for 5 days. The treated area may be covered with a sterile bandage or gauze dressing if desired.

Interaction

The effect of concurrent application of Retapamulin and other topical products to the same area of skin has not been studied.

Contraindications

Contraindicated in patients with hypersensitivity of any ingredient of this preparation.

Side Effects

Adverse effects: Application site irritation (<2% of patients may experience).

Pregnancy & Lactation

Pregnancy Category B. It is not known whether Retapamulin is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Retapamulin is administered to a nursing woman.

Precautions & Warnings

Local Irritation: In the event of sensitization or severe local irritation from Retapamulin, usage should be discontinued. Not for Systemic or Mucosal Use: Retapamulin is not intended for ingestion or for oral, intranasal, ophthalmic, or intravaginal use.

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

The information provided on this page is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. All brands listed might have copyright or trademark of their respective owners. Listed information may not be up-to-date or accurate. We do not guarantee the availability, quality, price or safety of any medication. Use at your own risk.

Available Brands

4 found

Brand	Strength	Type	৳
Pamulin Navana Pharmaceuticals Ltd.	1%	Ointment	-
Retabac Square Pharmaceuticals PLC	1%	Ointment	-
Retapex Incepta Pharmaceuticals Ltd.	1%	Ointment	-
Topibac Popular Pharmaceuticals Ltd.	1%	Ointment	-

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